Each tube contains: IMIDACLOPRID & MOXIDECTIN. Advocate for Cats Over 4 kgActive ingredientsImidacloprid 100g/L and moxidectin 10g/L solution for topical application onto cats. Advantage Multi ® for Cats (10% imidacloprid + 1% moxidectin) is a colorless to yellow ready-to-use solution packaged in single-dose applicator tubes for topical treatment of cats. Part hair between the shoulder blades until skin is visible. Background. Available in packs containing 3 and 6 pipettes of 0.4 and 0.8mL dose sizes.ActionImidacloprid exerts its effect by binding to post synaptic nicotinic receptors, blocking IMIDACLOPRID: 100 mg/mL (= 10.0%) MOXIDECTIN: 25 mg/mL for dogs (= 2.5%) 10 mg/mL for cats (= 1.0%) CHEMICAL CLASS of the active ingredient(s): Imidacloprid: NEONICOTINOID; Moxidectin: MACROCYCLIC LACTONE Do not use on canaries. For dogs, the corresponding “Endectrid for dogs” product, which contains 100 mg/ml imidacloprid and 25 mg/ml moxidectin, must be used. Lynxacarus radovskyi has been observed in cats in Malaysia; previously treatment with fipronil and moxidectin/imidacloprid spot‐on has been described.. For ferrets: Do not use Endectrid for large cats (0.8 ml) or Endectrid for dogs (any size). Dosage schedule for ferrets: one pipette of Advocate spot-on solution for small cats … imidacloprid / moxidectin) An overview of Advocate and why it is authorised in the EU . Advantage Multi® for Cats (10 % imidacloprid + 1 % moxidectin) is a colorless to yellow ready-to-use solution packaged in single-dose applicator tubes for topical treatment of cats. This is a common over-the-counter medication used to prevent fleas and heartworms in dogs as well as ear mites in cats. Administer the entire contents of the Advantage Multi ® for Cats tube that correctly corresponds with the body weight of the cat. The active ingredients in Advantage Multi for Cats are Imidacloprid and Moxidectin . Moxiclear spot-on solution for large cats. Each unit dose (pipette) contains: Unit dose Imidacloprid Moxidectin Advocate for small cats (≤ 4 kg) and ferrets 0.4 ml 40 mg 4 mg Advocate for large cats (> 4–8 kg) 0.8 ml 80 mg 8 mg . Common Precautions. The recommended minimum dose is 10 milligrams per kilogram imidacloprid and 1 milligram per kilogram moxidectin once a month by topical administration. Do not exceed the recommended dose. This product may also be used monthly for prevention of heartworm infection and to treat flea infestations in ferrets. Legal Category POM-V. Please refer to section 4.5. Parasitol Res 112 Suppl 1, 57-66 PubMed. The recommended minimum doses for cats are 10mg/kg body weight imidacloprid and 1.0mg/kg body weight moxidectin, equivalent to 0.1ml/kg body weight Endectrid for Cats. 4.4 Special warnings for each target species. Avoid any type of skin contact with the application site for 30 minutes following treatment with this topical flea medication. METHODS: Cats were experimentally inoculated with 300-800 third-stage larvae (L3). Available in packs of 3 or 6 . Weight of cat [kg] Pipette size to be used Volume [ml] Imidacloprid [mg/kg bw] Moxidectin [mg/kg bw] Directions for use: Use the top of the cap to break seal of tube. Imidacloprid plus moxidectin (Advantage® Multi for Cats, Bayer) was used as a positive control in both studies at the label dosage. For ferrets: Do not use Endectrid for large cats (0.8 ml) or Endectrid for dogs (any size). The formulation and dosage schedule are designed to provide a minimum of 4.5 mg/lb (10.0 mg/kg) imidacloprid and 0.45 mg/lb (1.0 mg/kg) moxidectin based on body weight. It will also treat and control whipworms in dogs and ear mites in cats. For Cats Over 4kg. Two studies were conducted to evaluate and compare the efficacy of imidacloprid + moxidectin and selamectin topical solutions against the KS1 flea strain infesting cats. Moxidectin also affects the nervous system in parasites and protects against heartworms. What is Advocate and what is it used for? Cautions. cats. In this study, the efficacy and safety of a treatment with the combination imidacloprid 10 %/ moxidectin 1.0 % spot-on (Advocate(®) spot-on for small cats and ferrets) was tested in 39 ferrets naturally infested with ear mites (Otodectes cynotis). The chemical name of imidacloprid is 1-[(6-Chloro-3-pyridinyl)methyl]-N-nitro-2-imidazolidinimine. Imidacloprid attacks the nervous system in insects, which causes impairment and subsequently death. Advocate is a medicine used on cats, ferrets and dogs suffering from, or at risk from, mixed parasitic infections (caused by several different types of parasites): Excipients: Benzyl alcohol . In this study, the efficacy and safety of a treatment with the combination imidacloprid 10 %/ moxidectin 1.0 % spot-on (Advocate® spot-on for small cats and ferrets) was tested in 39 ferrets naturally infested with ear mites (Otodectes cynotis). CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Dogs to use by or on the order of a licensed veterinarian. The study was performed as a multicentre, non-random … Advantage Multi for Cats (10% imidacloprid + 1% moxidectin) is a colorless to yellow ready-to-use solution packaged in single-dose applicator tubes for topical treatment of cats. Imidacloprid is a chloronicotinyl nitroguanidine insecticide. For Kittens, Small Cats & Ferrets up to 4 kg . Moxiclear is broad spectrum endectocide spot-on for very large cats (>4 ≤ 8 kg) containing imidacloprid and moxidectin. For cats, the recommended minimum dose is 4.5 mg/lb. Imidacloprid + moxidectin is applied between the shoulder blades every thirty days. Includes both imidacloprid (100g/L) and moxidectin (10g/L) : ... Moxiclear’s combination of Moxidectin and Imidacloprid has been shown to be safe in kittens when given from 9 weeks of age. Advantage Multi® (imidaclopid + moxidectin) Discover how Advantage Multi® has an innovative transdermal formula with imidacloprid + moxidectin for monthly flea protection. The formulation containing 10% imidacloprid and 1% moxidectin was 100% efficacious against the development of adult D. immitis infections when cats were treated 30 days after inoculation with third-stage larvae. Do not use on canaries. Each group comprised 8 animals and the treatment dose was 10 mg/kg bodyweight (bw) imidacloprid and 1 mg/kg bw moxidectin in each study. The recommended minimum doses are 10 mg/kg bodyweight imidacloprid and 1.0 mg/kg bodyweight moxidectin, equivalent to 0.1 ml/kg bodyweight Advocate for cats. Side effects are uncommon but may include irritation at the application site, or, if the medication is accidentally ingested, drooling, shaking, vomiting, and decreased appetite. 4.4 Special warnings for each target species. When used as directed on the label, imidacloprid with moxidectin is safe in most cats and ferrets. Do not let animal lick treated area; keep other pets and children away from treated animals until the area has dried (about 30 The treatment schedule should be based on the local epidemiological situation. (1.0 mg/kg) moxidectin once a month by topical administration. Resources. Advocate for cats contains 100 mg/ml imidacloprid and 10 mg/ml moxidectin.
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